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Why is proinsulin so called? How is insulin different from it?
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In mammals including humans, insulin is synthesized as a prohormone. Proinsulin contains an extra stretch called the C-peptide, (in addition to Chains A and B), which is absent in mature insulin and is removed during maturation into insulin.
Insulin on other hand consists of two short polypeptide chains - Chain A and Chain B which are linked together by disulphide bridges.
Insulin on other hand consists of two short polypeptide chains - Chain A and Chain B which are linked together by disulphide bridges.
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Question Text | Why is proinsulin so called? How is insulin different from it? |
Topic | Biotechnology and its Applications |
Subject | Biology |
Class | Class 12 |
Answer Type | Text solution:1 |
Upvotes | 118 |