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Mushroom is

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is a genus of mushroom containing both harmful and edible species.
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Scenario #1: Researchers want to investigate the efficacy and safety of using dual antithrombotic therapy (DOACs P2Y12 inhibitors) as compared to the standard triple antithrombotic therapy (VKA+Aspirin+P2Y12 inhibitors) [DAT TAT] in patients with atrial fibrillation (AF) who have undergone percutaneous coronary intervention (PCI). Upon sample size calculation and to determine at least a 10% reduction in the risk of major bleeding at a < 0.05 and power of 80%, the researchers estimated that they would need at least 1000 patients, 500 patients in each group, to assess the safety and efficacy outcomes. After designing the study and collecting all the needed data over one year of follow-up, the incidence of the outcomes of interest were found to be as presented in the table below: Data for the outcomes of interest: Safety Outcomes Groups Major Bleeding CRNMB AI-cause mortality DAT (n=500) 50 90 17 TAT (n=500) 70 120 25 Efficacy outcomes: Stroke, MI, Stent thrombosis DAT (n=500) 12 10 TAT (n=500) 10 Requirement for the assignment:
  1. Formulate two research questions based on the aim of the study.
  2. Formulate two alternative hypotheses (with null hypotheses) based on the aim of the study.
  3. Determine the type of statistical test that should be used to answer the research questions or hypotheses, and perform all the needed calculations for all outcomes and present your results.
  4. Provide screenshots of the results on the statistical software that you have used. You may use any statistical software to answer this question, such as PSPP, SPSS, Excel, STATA, R, PRISM, etc.
  5. Using findings from previous statistical tests, quantify and compare the effect of different treatment strategies on the specified outcomes, using the appropriate measures of effect.
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Question Text
Mushroom is
Updated OnMay 17, 2023
TopicBiological Classification
SubjectBiology
ClassClass 11
Answer TypeText solution:1 Video solution: 1
Upvotes155
Avg. Video Duration5 min