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How is ‘Rosie’ considered different from a normal cow ? Explain.

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Rosie is a transgenic cow.
Rosie produced human protein enriched milk, containing human alpha - lactalbumin. 
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Muscles are made up of many muscle fibers. Each muscle fiber is a multi-nucleated cell made by the fusion of many myocytes (muscle cells). A muscle fiber does not divide. A decrease in the number of myocytes through a decrease in cell division or an increase in myocyte apoptosis leads to fewer muscle fibers being formed and thus smaller muscles. A decrease in myocyte size through a decrease in cell growth leads to a decrease in the size of each muscle fiber and thus a consequent decrease in the muscle size. Myostatin dimerizes and binds to the activin receptor on myocytes, which brings together two action receptors and results in a conformational change in the cytoplasmic domain, resulting in activation of a tyrosine kinase in the activin receptor cytoplasmic domain, which phosphorylates the SMAD transcription factor and activates it. Activated SMAD and other enzymes activated by myostatin signaling transactivate genes that inhibit the cell cycle (p21), inhibit protein synthesis and degradation, or promote apoptosis. What effect does wild-type, or unmutated, myostatin have on the graph of the brightness of PI-stained myoblasts (DNA content) on the x-axis vs. number of myoblasts on the y-axis compared to the graph of PI-stained myoblasts with mutated myostatin? Select one:
  1. Higher number of cells at 4n only
  2. Lower number of cells at 2n, higher number at 4n and between 2.1n and 3.9n
  3. Higher number of cells at 2n, lower number at 4n and between 2.1n and 3.9n
  4. Higher number of cells between 2.1n and 3.9n only
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Question Text
How is ‘Rosie’ considered different from a normal cow ? Explain.
TopicBiotechnology and its Applications
SubjectBiology
ClassClass 12
Answer TypeText solution:1
Upvotes122