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The problem of double compared with single alkylation of ketones by iodomethane and base is mentioned in Section . Write a detailed mechanism showing how some double alkylation occurs even when only one equivalent each of the iodide and base is used. Suggest a reason why the enamine alkylation procedure solves this problem.
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Question Text | The problem of double compared with single alkylation of ketones by iodomethane and base is mentioned in Section . Write a detailed mechanism showing how some double alkylation occurs even when only one equivalent each of the iodide and base is used. Suggest a reason why the enamine alkylation procedure solves this problem. |
Topic | All topics |
Subject | Chemistry |
Class | Class 12 |