Texts: Can someone help answer these questions about these diagrams? Also, explain which approach yields more information and which is more versatile for experimental design. Using the pathway illustrated in Figure 16-37C, design an experiment to confirm your hypothesis that another protein in the pathway, protein Z, works downstream of Ras but upstream of protein Y. DEDUCED ORDER OF PROTEINS IN SIGNALING PATHWAY Signal molecule Plasma membrane CYTOSOL Active portal Active receptor tyrosine kinase SIGNALING Design an experiment to determine which tyrosines on the RTK are essential for PI3 kinase activation in Figure 16-32. What would you measure to determine activity? Survival signal Plasma membrane Inositol phospholipid EXTRACELLULAR SPACE CYTOSOL Phosphorylated inositol phospholipid Activated PI 3-kinase Activated RTK Protein kinase 1 Protein kinase 2 SIGNAL RELAYED ONWARD BY ACTIVATED AKt

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