A segment of DNA, AGCITCGAA, has lost first base. Assuming that translation starts from the next base the effect would bea. No change in polypeptide form b. Only first amino acid will be different c. A complete change in type and sequence of amino acids d. Last amino acid of polypeptide will be different

Sure, here are the step-by-step solutions: Given: A segment of DNA, AGCTTCGAA, has lost the first base. Step 1: Write out the DNA sequence: $AGCTTCGAA$ Step 2: Determine the codons in the sequence. A codon is a sequence of three DNA bases that codes for a specific amino acid. $\begin{array}{ccc}AGC& TTC& GAA\\ \text{serine}& \text{phenylalanine}& \text{glutamic acid}\end{array}$ Step 3: Determine the effect of losing the first base. Since codons are read in a contiguous manner, losing the first base would shift the reading frame and change the sequence of codons: $\begin{array}{ccc}GCT& TCG& AA\\ \text{alanine}& \text{serine}& \text{stop}\end{array}$ Step 4: Determine the effect on the sequence of amino acids. The new codons code for different amino acids, and the last codon is a stop codon, which terminates the translation process: $\begin{array}{ccccc}\text{serine}& \text{glutamic acid}& \text{alanine}& \text{serine}& \text{stop}\end{array}$ Step 5: Summarize the effect. Losing the first base in the DNA sequence would cause a complete change in the type and sequence of amino acids that are coded for, resulting in a truncated protein due to the premature stop codon.