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Why do children cured by enzyme-replacement therapy for adenosine deaminase deficiency need periodic treatment ?
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They need periodic treatment because it is not a completely curative method. In this method, a functional ADA-cDNA is injected into the patient’s lymphocytes using a retroviral vector. Since, lymphocytes have a definite life cycle, there is a need for periodic infusion of genetically engineered lymphocytes (having ADA) into the patient.
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| Question Text | Why do children cured by enzyme-replacement therapy for adenosine deaminase deficiency need periodic treatment ? |
| Topic | Biotechnology and its Applications |
| Subject | Biology |
| Class | Class 12 |
| Answer Type | Text solution:1 |
| Upvotes | 123 |
