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What is gene therapy? Illustrate using the example of adenosin
Biology
Biology

Class 12

NCERT

Publisher:
NCERT
Subject:
Biology
1

Chapter 1: Reproduction in Organisms

18 questions

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2

Chapter 2: Sexual Reproduction in Flowering Plants

18 questions

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3

Chapter 3: Human Reproduction

21 questions

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4

Chapter 4: Reproductive Health

12 questions

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5

Chapter 5: Principles of Inheritance and Variation

16 questions

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6

Chapter 6: Molecular Basis of Inheritance

14 questions

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7

Chapter 7: Evolution

10 questions

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8

Chapter 8: Human Health and Disease

17 questions

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9

Chapter 9: Strategies for Enhancement in Food Production

12 questions

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10

Chapter 10: Microbes in Human Welfare

15 questions

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11

Chapter 11: Biotechnology: Principles and Processes

12 questions

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12

Chapter 12: Biotechnology and its Applications

10 questions

Q1
What are Cry proteins? Name an organism that produce it. How has man exploited this protein to his benefit?
Q2
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
Q3
Digrammatically represent the experimental steps in cloning and expressing an human gene (say the gene for growth hormone) into a bacterium like E. coli ?
View all question
13

Chapter 13: Organisms and Populations

17 questions

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14

Chapter 14: Ecosystem

13 questions

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15

Chapter 15: Biodiversity and Conservation

10 questions

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16

Chapter 16: Environmental Issues

11 questions

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Question
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What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.

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Gene therapy is the process of introduction of DNA into an organism e.g. human beings in order to treat a disease. It is used to replace a missing gene product or to correct mutant alleles. ADA is an autosomal-recessive inherited disorder that occurs due to defective adenosine deaminase (ADA) enzyme. Please with this enzyme deficiency suffer from severe combined immunodeficiency (SCID) conditions. Human gene therapy trial can be used for ex vivo introduction of functional ADA gene in bone marrow cells of the patient, suffering from SCID. For this process, an engineered retrovirus containing a functional ADA gene is used to transfer the ADA gene into stem cells isolated from the patient with SCID. The treated cells or modified cells with the good ADA gene are reintroduced into the patient’s marrow.
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Question Text
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
TopicBiotechnology and its Applications
SubjectBiology
ClassClass 12
Answer TypeText solution:1
Upvotes13