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A researcher prepared two DNA sequences corresponding to A & B
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A researcher prepared two DNA sequences corresponding to A & B, chain of insulin & introduced them in plasmid of E. Coli to produce insulin chains. He produced A & B chain separately, Extracted them but forget to combined them by creating disulphide bond. Now this genetically engineered formed insulin was taken by a diabetic patient :
(i) This genetically engineered insulin would not work in succesful manner.
(ii) Patient would not cope up with diabetes via use of this type of insulin.
(iii) That type of insulin work in a better way & patient recover sooner.
(iv) It might caused reactions in the body.
Choose the incorrect option.

A
(i), (ii) and (iii)

B
Only (iv)

C
(ii), (iii) and (iv)

D
Only (iii)

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Updated on: May 19, 2023

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A researcher prepared two DNA sequences corresponding to A & B, chain of insulin & introduced them in plasmid of E. Coli to produce insulin chains. He produced A & B chain separately, Extracted them but forget to combined them by creating disulphide bond. Now this genetically engineered formed insulin was taken by a diabetic patient :
(i) This genetically engineered insulin would not work in succesful manner.
(ii) Patient would not cope up with diabetes via use of this type of insulin.
(iii) That type of insulin work in a better way & patient recover sooner.
(iv) It might caused reactions in the body.
Choose the incorrect option.
12 mins ago
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Text SolutionText solutionverified iconVerified

Human insulin is a 51-amino acid peptide hormone with a molecular weight of 5808 Da. It is composed of an A-chain (21 amino acids) and a B-chain (30 amino acids), which are linked by two disulfide bonds. Insulin is synthesized in pancreatic β-cells and secreted in response to elevated blood glucose levels. If chain A & B of insulin are not combined by disulphide bonds, than it will not work in human body and might cause undesirable effects.
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Question Text
A researcher prepared two DNA sequences corresponding to A & B, chain of insulin & introduced them in plasmid of E. Coli to produce insulin chains. He produced A & B chain separately, Extracted them but forget to combined them by creating disulphide bond. Now this genetically engineered formed insulin was taken by a diabetic patient :
(i) This genetically engineered insulin would not work in succesful manner.
(ii) Patient would not cope up with diabetes via use of this type of insulin.
(iii) That type of insulin work in a better way & patient recover sooner.
(iv) It might caused reactions in the body.
Choose the incorrect option.
Updated OnMay 19, 2023
TopicBiotechnology and its Applications
SubjectBiology
ClassClass 12
Answer TypeText solution:1 Video solution: 2
Upvotes337
Avg. Video Duration3 min